SHANGHAI, March 18 (Xinhua) -- A Chinese research team has developed a multicellular scaffold based on inorganic bioceramics for treating tendon-to-bone injuries.
Restriction of motor activity due to loss of natural structure is a major cause of decreased life quality in patients suffering from tendon-to-bone injuries.
To solve this problem, the research team, led by the Shanghai Institute of Ceramics (SIC) of the Chinese Academy of Sciences, combined manganese silicate (MS) nanoparticles with tendon/bone-related cells to construct an immunomodulatory multicellular scaffold to achieve integrated tendon-to-bone regeneration.
The scaffold not only demonstrated diverse biological activities in vitro, but also achieved immune regulation, multi-tissue integration regeneration and motor function recovery in a variety of animal models of rotator cuff injury.
The study provides a new concept for achieving immunomodulation and integrated regeneration of tendon-bone and other tissue interfaces, said Wu Chengtie with the SIC, who led the research.
The study was recently published in the journal Science Advances.
(Editor:Fu Bo)
Supreme Court to decide on Trump federal prosecution immunity
Selfless Dedication — from Generation to Generation
Tensions simmer near a shoal both China and the Philippines claim — Radio Free Asia
Exploring Liu Zongyuan's Life, Great Achievements
A More Beautiful World Built, Shared by All
Epiphanny Prince retires from basketball after a 14
Libo: 'Emerald on the Earth's Belt'
Analysts: US missile deployment expected to assist Philippines’ defense — Radio Free Asia
Reform, Opening Up Brings China Closer to the World