SHANGHAI, March 18 (Xinhua) -- A Chinese research team has developed a multicellular scaffold based on inorganic bioceramics for treating tendon-to-bone injuries.
Restriction of motor activity due to loss of natural structure is a major cause of decreased life quality in patients suffering from tendon-to-bone injuries.
To solve this problem, the research team, led by the Shanghai Institute of Ceramics (SIC) of the Chinese Academy of Sciences, combined manganese silicate (MS) nanoparticles with tendon/bone-related cells to construct an immunomodulatory multicellular scaffold to achieve integrated tendon-to-bone regeneration.
The scaffold not only demonstrated diverse biological activities in vitro, but also achieved immune regulation, multi-tissue integration regeneration and motor function recovery in a variety of animal models of rotator cuff injury.
The study provides a new concept for achieving immunomodulation and integrated regeneration of tendon-bone and other tissue interfaces, said Wu Chengtie with the SIC, who led the research.
The study was recently published in the journal Science Advances.
(Editor:Fu Bo)
California cops, firefighters, and utility workers are earning up to $800k a year in overtime pay
Junior of Revolutionaries Inherits, Promotes Family's 'Red Gene'
Junior of Revolutionaries Inherits, Promotes Family's 'Red Gene'
Analysis: The IndyCar season has just started but free agency is in full swing after only 2 races
Uygur Woman Shows Charm of Xinjiang Through Fabulous Dance
Zhang Lan: Helping Miao Women Use Fingertips to Achieve Prosperity
Zheng Zhenxiang: A Life Dedicated to Archeology
Kid Cudi says he broke 'something in my heel' after falling off stage during his last
Lifelong Passion for Painting Persists